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Cytochromes P450 are a class of metalloproteins which are responsible for electron transfer in a wide spectrum of reactions including metabolic biotransformation of endogenous and exogenous substrates. The superfamily of cytochromes P450 consists of families and subfamilies which are characterized by a specific structure and substrate specificity. Cytochromes P450 family 1 (CYP1s) play a distinctive role in the metabolism of drugs and chemical procarcinogens. In recent decades, thesedoi:10.1155/2018/3924608 pmid:30147715 pmcid:PMC6083639 fatcat:5hdcm4kyo5bd5aqqdhkjy3hpgi