Coexistence of Systemic Lupus Erythematosus and Inflammatory Bowel Disease

Toru Shizuma
2012 Internal Medicine Open Access  
IBD subgroup: cases of SLE and UC: In a controlled study, 6.6% patients with UC had at least one additional autoimmune disorder. Conversely, only 2% healthy controls and 1.9% CD patients had at least one autoimmune disorder [4, 22, 23] . The rate of concurrent SLE and UC has been reported to be 0%-0.5% [22] , whereas the incidence of UC in SLE patients is approximately 0.4% (2/520) [2,3,12,23]. Abstract The coexistence of systemic lupus erythematosus (SLE) and inflammatory bowel disease (IBD)
more » ... rare. This report reviews the English and Japanese literature covering the reported cases of concomitant SLE and IBD. We identified 17 cases of concomitant SLE and Crohn's disease (CD) and 13 cases of concomitant SLE and ulcerative colitis (UC). We observed that many patients (19/28) developed SLE before IBD. Furthermore, SLE was almost never active at presentation of IBD, and flares of SLE were uncommon after IBD development.
doi:10.4172/2165-8048.1000140 fatcat:wr4npi2vt5c7vnsfwuqe4ammca