A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2019; you can also visit the original URL.
The file type is application/pdf
.
Hybridization Efficiency of Molecular Beacons Bound to Gold Nanowires: Effect of Surface Coverage and Target Length
2010
Langmuir
Surface-bound nucleic acid probes designed to adopt specific secondary structures are becoming increasingly important in a range of biosensing applications but remain less well characterized than traditional single-stranded probes, which are typically designed to avoid secondary structure. We report the hybridization efficiency for surfaceimmobilized hairpin DNA probes. Our probes are molecular beacons, carrying a 3 0 dye moiety and a 5 0 thiol for attachment to gold nanowires, which serve as
doi:10.1021/la1031703
pmid:21038880
pmcid:PMC2994276
fatcat:bgb37plcmzdvloz3qebodzhhhi