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Yokukansan increases serum Brain-derived neurotrophic factor (BDNF) levels in Gunn rat
2014
Journal of brain science
Brain-derived neurotrophic factor (BDNF) is expressed at high levels in the hippocampal dentate gyrus (DG), and decreased levels of BDNF have been implicated in the pathophysiology of schizophrenia (SCZ). We have previously reported that yokukansan (YKS), which is a traditional Japanese medicine, is effective for SCZ and promotes neurogenesis in the DG of Gunn rats, an animal model of SCZ. In this study, we investigated the effect of YKS on serum BDNF levels in Gunn rats. The results showed
doi:10.20821/jbs.44.0_34
fatcat:5opqvxx2arc5thl34fmjjva6ei