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Scutellaria baicalensis Georgi induces caspase-dependent apoptosis via mitogen activated protein kinase activation and the generation of reactive oxygen species signaling pathways in MCF-7 breast cancer cells
Molecular Medicine Reports
Scutellaria baicalensis Georgi extract (SBGE) is used in traditional herbal medicine and has also been used clinically to ameliorate the symptoms of various inflammatory diseases and cancer. In women, breast cancer is one of the most common diseases and numerous women succumb to it. The present study was undertaken to investigate the mechanism responsible for the SBGE-induced apoptosis of MCF-7 human breast cancer cells. SBGE was administered to cells at concentrations between 100 and 500doi:10.3892/mmr.2017.6798 pmid:28627691 fatcat:3oao3jqjbjdt3keqwllfz5ncoy