Effects of Melatonin Suplementation in Human Pathologie: A Systematic Review

E Mármol Peis, GA Cañadas-De la Fuente, JL Gómez-Urquiza, R Fernandez-Castillo, F Ocaña Peinado, R Guisado Barrilao, IM Guisado Requena
2017 West Indian medical journal  
Objectives: to analyse the main effects of melatonin dietary supplementation in different pathologies. Method: systematic review related to the use of melatonin as a dietary supplement and its effects on PubMed, CINAHL, Scopus, ProQuest Health and Medical Complete, Scielo and Dialnet databases. Results: the 613 obtained articles at baseline were finally reduced to 19 after the application of inclusion and exclusion criteria and the reverse search. Melatonin supplementation has shown its
more » ... in sleep disorders, aging, various chronic diseases and anthropometry. Conclusions: the known benefits of melatonin are regulating the sleep-wake cycle and preventing oxidative stress of multiple health-disease processes. However, more research is needed to determine its applicability in numerous pathologies.
doi:10.7727/wimj.2016.500 fatcat:nkqrxsdmdbfhraaug7rmb7s7de