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Differential expression of TRAF5 in amyotrophic lateral sclerosis
[post]
2022
unpublished
Neurodegenerative diseases that affect the motor neurons, including amyotrophic lateral sclerosis (ALS), have little treatment options and are generally rapidly fatal (1, 2). We harnessed the power of unbiased, whole transcriptome differential gene expression analysis, utilizing primary patient cells and tissues to discover genes whose expression defines ALS using published microarray data (3, 4). We found significant differential expression of TRAF5, encoding TNF receptor-associated factor 5,
doi:10.31219/osf.io/bu3wa
fatcat:pxzaq655jjfwzalme5sv72ugyy