to this alleged malarial sequela, and says that the dispute has been of the warmest. Dr. Osier in his writings has insisted upon "the necessity of considering otheretiologic factors, e.g., alcohol, syphilis, tuberculosis, even when malaria appears to stand in a direct relation to the disease. Of the many persons who have had malaria, very few of them have developed cir¬ rhosis of the liver afterward. Dr. Welch states that in his