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The low density lipoprotein particle is the major transporter of cholesterol around the body and has been shown to be a strong independent risk factor for atherosclerotic events. This review discusses the normal and abnormal metabolism of low density lipoprotein (LDL). Mechanisms by which LDL causes atherosclerosis are discussed with particular reference to the importance of alteration in LDL composition including attachment of other proteins to the circulating LDL particle.doi:10.2174/1876506801205010013 fatcat:mxcixi63jfd7jnpmdxudfnuubm