Patients with chronic hepatitis C undergoing watchful waiting: Exploring trajectories of illness uncertainty and fatigue

Keyur Patel, Julie Barroso, Lawrence Landerman, Merle H. Mishel, John McHutchison, Donald E. Bailey, Jacqui Richmond, Andrew J. Muir, Richard Sloane
2010
We identified trajectories of illness uncertainty in chronic hepatitis C patients and examined their association with fatigue levels during 12 months of disease monitoring without treatment (watchful waiting). Sixty-two men and 63 women completed uncertainty and fatigue measures. Groups were formed by uncertainty scores (high, medium, low) at baseline. Baseline fatigue levels were higher in the high uncertainty group than in the medium and low groups. Over time, uncertainty levels did not
more » ... evels did not change. Fatigue levels in the low uncertainty group remained constant, increased in the medium, and decreased in the high groups. Findings suggest that uncertainty and fatigue do not remit spontaneously. Being aware of this may help nurses identify those patients needing support for these two concerns.
doi:10.17615/f046-nm72 fatcat:ailhgpvt4rdf5h3ar7zoxj4dby