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Identifying reliable subnetwork markers in protein-protein interaction network for classification of breast cancer metastasis
2010
2010 IEEE International Conference on Acoustics, Speech and Signal Processing
Due to the inherent measurement noise in microarray experiments, heterogeneity across samples, and limited sample size, it is often hard to find reliable gene markers for classification. For this reason, several studies proposed to analyze the expression data at the level of groups of functionally related genes such as pathways. One practical problem of these pathway-based approaches is the limited coverage of genes by known pathways. To overcome this problem, we propose a new method for
doi:10.1109/icassp.2010.5495633
dblp:conf/icassp/SuY10
fatcat:63q2oqbehnaqbapn7jwxj5xfgq