A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2021; you can also visit the original URL.
The file type is
The talk introduces Petri net (PN) basics and discusses their application to modeling signaling pathways. We explain our wok on the TNFR1 signaling pathway focusing on different outcomes for the cell, its survival, apoptosis and necroptosis. We applied the PN formalism and invariant-based analysis. Based on experimental findings in the current literature, we constructed a PN model in terms of detailed molecular reactions for the molecular players, protein complexes, post-translationaldoi:10.5281/zenodo.4462577 fatcat:mbwnhrzu5jfx3cmsbxaki4xga4