Efficacy and Safety of Intralesional Bleomycin for Treatment of Lymphangioma: Report from a Tertiary Care Hospital of Bihar

Dr. MD Sarfaraz Nawaz, Dr. Aditya Anand, Dr. Kumar Shubham
2022 International journal of pharmaceutical sciences review and research  
Lymphangioma is a benign tumor of lymphatic vessels, with 75% cases occurring in head and neck. Surgical excision is the traditional management. Intralesional sclerotherapy has become a method of treatment for lymphangiomas in children. A retrospective clinical trial was conducted to evaluate the efficacy of intralesional bleomycin sclerotherapy (IBS) in the treatment of lymphangiomas in children. Methodology: A prospective study was conducted by the Department of General Surgery of MGM Medical
more » ... College, Kishanganj, Bihar. Study was commenced after getting the ethical approval from the Institutional ethical committee. The period of data collection was 2 years that is from October 2019 to September 2021. The response of IBS was assessed clinically and on the basis of color Doppler USG. Results: 36 patients of lymphangioma were included in the study. 63.9% patients were seen before 1 year of age. Of all, 75% of the cases that is 27 patients had cystic hygroma, 3 were cavernous, and 6 were of mixed type. The neck region was the most common site with 25 (69.4%) patients. 19.4% required single dose. 11 patients developed side effects. Conclusion: Complications can also occur postoperatively o
doi:10.47583/ijpsrr.2022.v77i01.001 fatcat:cqbfw2qfgzdtfayjbg4dgn246i