Comparison of single cell transcriptomics technologies and their application to investigate cellular heterogeneity in healthy and diseased lung

Timo Benedikt Trefzer
However, until recently, our ever-improving capability to characterise the molecular phenotype of cells was not applicable at the level of single cells, because the amount of material required for NGS technologies far exceeded the typical quantity of DNA or RNA found in one cell and technologies to capture and amplify nucleic acids at single cell resolution were lacking. Studies of cellular genomes and transcriptomes
doi:10.11588/heidok.00031433 fatcat:k75ubywflvdk7llydlyjvgdtu4