Iron deposition in Parkinson's disease by quantitative susceptibility mapping

Qiqi Chen, Yiting Chen, Yue Zhang, Furu Wang, Hongchang Yu, Caiyuan Zhang, Zhen Jiang, Weifeng Luo
<span title="2019-05-22">2019</span> <i title="Springer Science and Business Media LLC"> <a target="_blank" rel="noopener" href="https://fatcat.wiki/container/hus553nnwfhsbi2wiivfjdwxru" style="color: black;">BMC Neuroscience</a> </i> &nbsp;
Patients with Parkinson's disease (PD) have elevated levels of brain iron, especially in the nigrostriatal dopaminergic system. The purpose of this study was to evaluate the iron deposition in the substantia nigra (SN) and other deep gray matter nuclei of PD patients using quantitative susceptibility mapping (QSM) and its clinical relationship, and to explore whether there is a gradient of iron deposition pattern in globus pallidus (GP)-fascicula nigrale (FN)-SN pathway.
<span class="external-identifiers"> <a target="_blank" rel="external noopener noreferrer" href="https://doi.org/10.1186/s12868-019-0505-9">doi:10.1186/s12868-019-0505-9</a> <a target="_blank" rel="external noopener" href="https://www.ncbi.nlm.nih.gov/pubmed/31117957">pmid:31117957</a> <a target="_blank" rel="external noopener" href="https://pubmed.ncbi.nlm.nih.gov/PMC6532252/">pmcid:PMC6532252</a> <a target="_blank" rel="external noopener" href="https://fatcat.wiki/release/zle6bqk26vax5napmnlj2hvn2u">fatcat:zle6bqk26vax5napmnlj2hvn2u</a> </span>
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