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Forest tree species are highly vulnerable to the effects of climate change. As sessile organisms with long generation times, their adaptation to a local changing environment may rely on epigenetic modifications when allele frequencies are not able to shift fast enough. However, the current lack of knowledge on this field is remarkable, due to many challenges that researchers face when studying this issue. Huge genome sizes, absence of reference genomes and annotation, and having to analyze hugedoi:10.3389/fpls.2021.797958 pmid:35058957 pmcid:PMC8764141 fatcat:kn2vheackzd4tizipbjmar775e