Family history and the natural history of colorectal cancer: systematic review

Nora B. Henrikson, Elizabeth M. Webber, Katrina A. Goddard, Aaron Scrol, Margaret Piper, Marc S. Williams, Doris T. Zallen, Ned Calonge, Theodore G. Ganiats, A. Cecile J.W. Janssens, Ann Zauber, Iris Lansdorp-Vogelaar (+2 others)
2015 Genetics in Medicine  
Conclusion: Stratification based on polygenic and/or multifactorial risk assessment may mature to the point of displacing family historybased approaches, but for the foreseeable future, family history may remain a valuable clinical tool for identifying individuals at increased risk for CRC.
doi:10.1038/gim.2014.188 pmid:25590981 pmcid:PMC4955831 fatcat:j3c3aggq4fecpl6stkxe64foza