Relationship between subclinical hypothyroidism and serum homocysteine concentration in premenopausal women
Premenopozlu kadınlarda subklinik hipotiroidi ve homosistein düzeyleri ilişkisi

Ayfer Aydoğdu Çolak
2013 Journal of Clinical and Experimental Investigations  
Objective: In our study we aimed to examine serum homocysteine levels of patients without thyroid dysfunctions who have high serum anti thyroid peroxidase (anti-TPO) levels and patients with subclinical hypothyroidism who have high serum thyroid stimulating hormone (TSH) and anti-TPO levels. Methods: One hundred and seven premenopause female outpatients who referred to endocrine clinic of our hospital were included in our study. We generated 3 groups. First group (Control) consists of 53 (50%)
more » ... atients between the ages of 30-40 years. Second group (Euthyroid) consists of 31 (29%) patients between the ages of 26-49. Third group (Subclinical Hypothyroidism) consists of 23 (21%) patients between the ages of 33-53 years. Serum total cholesterol, triglycerides, high density lipoprotein (HDL) levels were measured by Olympus 2700 autoanalyzer. Serum TSH, free T4, anti-TPO and homocysteine levels were measured by Siemens Immulite 2000 autoanalyzer. Çolak ve ark. Kadınlarda subklinik hipotiroidi -homosistein düzeyleri ilişkisi 294
doi:10.5799/ahinjs.01.2013.03.0287 fatcat:tbbwlj5d7zfcxluxd6faqqdajm