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Fc-Binding Ligands of Immunoglobulin G: An Overview of High Affinity Proteins and Peptides
2016
Materials
The rapidly increasing application of antibodies has inspired the development of several novel methods to isolate and target antibodies using smart biomaterials that mimic the binding of Fc-receptors to antibodies. The Fc-binding domain of antibodies is the primary binding site for e.g., effector proteins and secondary antibodies, whereas antigens bind to the Fab region. Protein A, G, and L, surface proteins expressed by pathogenic bacteria, are well known to bind immunoglobulin and have been
doi:10.3390/ma9120994
pmid:28774114
pmcid:PMC5456964
fatcat:koid5udcebbpzeppblhapjih3e