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Personalized medicine for cancer entails tailoring therapy for each patient based on unique features of the patient's tumor; physiologic, molecular, genetic and epigenetic. Our ability to molecularly characterize tumor cells has increased dramatically and shown that there are significant differences between samples from patients with the same tumor type. Given this extensive variability in mutations and pathways driving tumors in patients, seeking a single bullet is an unrealistic approach fordoi:10.4103/2152-7806.151351 pmid:25722938 pmcid:PMC4338492 fatcat:ra3wykdepnecjielkk3b5yyxiy