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Pathophysiology and clinical management of pain in Parkinson's disease: Differences in efficacy of dopamine agonists and deep brain stimulation
Although different types of pain may be present from the early stage of Parkinson's disease (PD), musculoskeletal pain related to an impaired motor status is most commonly encountered in clinical practice. Levodopa is widely for the treatment of PD and can substantially improve symptoms. However, prolonged treatment with levodopa can induce serious motor complications, which in turn may trigger or aggravate pain. It has been reported that dopamine agonists, when used in conjunction withdoi:10.11154/pain.31.135 fatcat:wwx6b2wwavey3duc4vegcafgrm