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Isolation and expression of UB05, a Plasmodium falciparum antigen recognised by antibodies from semi-immune adults in a high transmission endemic area of the Cameroonian rainforest
Clinical Chemistry and Laboratory Medicine
Antibodies in adults living in malaria endemic areas that target specific parasite antigens are implicated in protective immunity to infection and disease. This study aimed to identify, isolate and characterise targets of protective immunity in malaria. A Plasmodium falciparum antigen termed UB05 (Genbank Accession Number DQ235690: PlasmoDB PF10_ 0372) that had been isolated by immunoscreening with semi-immune sera was studied. Methods: Polymerase chain reaction, sequencing and bioinformaticsdoi:10.1515/cclm.2009.255 pmid:19728857 fatcat:fm7egchmkrhozmzlze6gj2n3gu