137 Myocarditis in pediatric lupus: A clinical conundrum

Nameirakpam Johnson, Deepti Suri, Anju Gupta, Amit Rawat, Surjit Singh
2019 Abstracts   unpublished
adjusting for age, sex, disease duration, total cumulative corticosteroid dose, and top 10 PCs as covariates. In further analysis of SLE patients with AVN compared with SLE patients without AVN treated by a high corticosteroid [cumulative dose >20 g], the AVN-risk loci were highly expressed in fibroblasts (p=8.78×105) and musculoskeletal system (p=1.13×104) using DEPICT. Conclusions These findings provide genetic evidence that pathway of fibroblasts are relevant to osteonecrosis. Individual
more » ... tic risk for the development of AVN should be assessed prior to treatment for SLE. Funding Source(s): None
doi:10.1136/lupus-2019-lsm.137 fatcat:3l524jplczdrxf4b4yiuj72phy