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Quantitation of anticancer drugs – Cyclophosphamide and ifosfamide in urine and water sewage samples by gas chromatography–mass spectrometry
International Journal of Occupational Medicine and Environmental Health
Objectives: Cyclophosphamide (CP) and ifosfamide (IF) are effective anti-cancer drugs but their genotoxicity can harm everyone contacting them occupationally or environmentally. Therefore, a sensitive method for monitoring their amounts in biological and environmental samples is needed. This has aimed to develop a method for analyzing these drugs in urine and water sewage samples. Material and Methods: The drug spiked samples were extracted, derivatized, and analyzed by gas chromatography-massdoi:10.13075/ijomeh.1896.00773 pmid:27518890 fatcat:2gzmgcdo55bidf4b3f7yge2q4a