Successful Management of Severe Bleeding After Redo Cardiac Transplantation with Recombinant Activated Factor VII

Rosina Albisinni
2012 Journal of Clinical Case Reports  
Heart transplant recipients who are on a prior aggressive anticoagulant or antiplatelet treatment may experience severe post-operative bleeding. We describe a case of bleeding after cardiac transplantation which was refractory to standard treatment and was eventually managed with the off-label use of recombinant activated coagulation factor VII. The relevance of this approach in terms of patient survival as well as graft preservation is discussed.
doi:10.4172/scientificreports.225 fatcat:bxzbdt6ikjg3fozdf55ip5hgcu