Elevated Urinary Matrix Metalloproteinase-7 Detects Underlying Renal Allograft Inflammation and Injury

Julie Ho, David N. Rush, Oleg Krokhin, Mihaela Antonovici, Ang Gao, Jennifer Bestland, Chris Wiebe, Brett Hiebert, Claudio Rigatto, Ian W. Gibson, John A. Wilkins, Peter W. Nickerson
2016 Transplantation  
The authors declare no conflicts of interest. J.H. designed the study, attained the operating funds, supervised the experimental work and analysis, and wrote the article. D.R. contributed to collection of the clinical database/urine bio-bank and writing the article. O.K. supervised the mass spectrometry based proteomic analysis and writing the article. M.A. performed the mass spectrometry based proteomic analysis and assisted with writing the mass spectrometry methods in the article. A.G.
more » ... article. A.G. performed all the urinary MMP7 enzymelinked immunosorbent assay assays. C.W. assisted with the statistical analysis and contributed to writing the article. B.H. performed the statistical analysis and contributed to writing the article. C.R. supervised the statistical analysis and assisted with the article regarding the statistical methodology section. I.G. evaluated the histopathology and contributed to writing the article. J.A.W. supervised the mass spectrometry based proteomic analysis and writing the article. P.N. contributed to collection of the clinical database/urine bio-bank. He also contributed to the study design, data analysis and writing the article.
doi:10.1097/tp.0000000000000867 pmid:26906940 fatcat:5xvdeyf7kjaprnvmmicsf3exda