Objective: This study evaluated the use of antibiotics in the treatment of patients with acute respiratory infection (ARI) in the outpatients installation in Bunda Thamrin General Hospital, Medan. Methods: This prospective descriptive cohort study analyzed the use of antibiotics provided to patients with ARI using Indonesian universal health coverage known as Badan Penyelenggara Jaminan Sosial claims (n=130) in outpatients installations from March to May 2018. The characteristics of the

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... were organized and descriptively analyzed in Excel and SPSS programs. The antibiotics provided were grouped according to the Anatomical Therapeutical Chemical code and class; then, the dosage form, defined daily dose (DDD) units, was converted into milligrams. DDD calculation was done by dividing the total DDD usage with the total number of patients. Results: Mean age of the patients was 32.12±10.579 years. The highest quantity of antibiotic use in DDD/1000 patients-day units was cefixime reaching 1,897.435 mg DDD KPRJ. Conclusions: Cefixime was the most widely available antibiotic for the treatment of ARI patients.