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Paraoxonase1 and its relationship with Parkinson's disease
2019
Brain and Nerves
This study reviews current understanding of relationship of paraoxonase1 polymorphisms and activity of paraoxonase1 in Parkinson's Disease (PD). Paraoxonase 1 (PON1) is involved in the detoxification of insecticides and pesticides and metabolisms of these toxins. Two polymorphisms within the gene affect the activity of paraoxonase. In One of them a methionine replaces with leucine at position 54 (M54L) and the other a glutamine change to arginine variant at position 192 (Q192R). There are some
doi:10.15761/jbn.1000120
fatcat:5guwn3dyd5azhkfb7psdcwzgfi