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A fast microfluidic device to measure the deformability of red blood cells
[article]
2019
bioRxiv
pre-print
We report a microfluidic device to determine the shear elastic modulus and the Young's modulus of red blood cells (RBCs). Our device consists of a single channel opening into a funnel, with a semi-circular obstacle placed at the mouth of the funnel. As a RBC passes the obstacle, it deflects from its original path. Using populations of artificially-stiffened RBCs, we show that the stiffer RBCs deflect more compared to the normal RBCs. We use calibration curves obtained from numerical simulations
doi:10.1101/644161
fatcat:3v57ktlcyjccdaaca3b3xgpelq