Clinical case study: Effectiveness of a multidisciplinary program in metabolic disorders reduction

Priscila Moreira, Catharina C.J. Paiva, Carlos D. Magnoni, Cristiane Kovacs
2015 BBA Clinical  
with stable coronary disease (documented by coronary angiography, n = 7); and healthy controls (n = 7), matched by age and sex. B1 cells were characterized by CD20+CD27+CD43+CD70− and B2 cells were identified by CD19+CD23+;both by flow-cytometry. Results: B2 cells were more prevalent among CAD subjects (AMI and stable CHD; n = 14) than controls (p = 0.05). In addition, negative correlation was observed among B1 cells and age (p = 0.05). Conclusion: Preliminary data suggest that there is a
more » ... at there is a subtype of lymphocytes in humans (B1) that are negatively correlated with age. An imbalance between B1 and B2 cells emerges as important aspect of immune responses and possible new target for the prevention or treatment of atherosclerosis.
doi:10.1016/j.bbacli.2015.05.026 fatcat:ajnkiyl24rbn7nifrtwd5mjacq