誗 AIM: To study the retinal function in patients with diabetic macular edema after photocoagulation. 誗METHODS: A total of 30 eyes in 19 patients with diabetic macular edema (DME) , who were diagnosed through fundus fluorescein angiography, consecutively recruited from March 2010 to March 2014 and were treated with macular grid pattern photocoagulation. Multifocal electroretinogram (mfERG) system (version 3. 15) was performed before and after photocoagulation therapy for 3mo. All data were

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... tically analyzed. 誗RESULTS: The amplitude densities of aware and b-ware for the fovea increased after macular grid pattern photocoagulation therapy, and there were significantly changes relative to its preoperation (t =-3郾 7683, P<0. 01; t =-3. 6570, P< 0. 01). No remarkable changes in the latency of aware and b-ware of fovea were measured before and after photocoagulation (t = 1. 7103, P>0. 05; t = 1. 5623, P>0郾 05). Compared with pretreatment, the amplitude densities of aware and b-ware at macular were statistically larger (t = 4郾 8337, P<0. 01; t =-2. 0376, P<0. 05). The latency of a-wave and b-wave at macular was significant longer after treatment (t =-2. 1892, P < 0. 05; t =-3. 5024, P < 0. 01). There were no significant differences in the amplitude densities of aware and b-ware at paramacular after therapy (t =-1. 4387, P>0. 05; t =-0. 1766, P>0. 05). It was significant longer in the latency of a-wave and b-wave at paramacular after photocoagulation (t =-2. 0905, P<0. 05; t =-2. 5646, P<0. 05).