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Involvement of the midbrain and hindbrain (MHB) in the various groups of lissencephalies was examined in an MRI study of 111 patients (aged 1 day to 32 years; mean 5 years 4 months) studied at University of California San Francisco, and centers in France, Belgium, and Turkey. The three major groups of lissencephaly (cLIS or LIS type 1; vLIS or variant LIS; and CBSC, cobblestone complex or LIS type 2) showed significant differences in the appearance and severity of associated MHB malformations;doi:10.15844/pedneurbriefs-23-3-1 fatcat:j2i3dpv2ezcxzbi33jf6vdlwpe