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Integrins require an activation step before ligand binding and signaling that is mediated by talin and kindlin binding to the β integrin cytosolic domain (β-tail). Conflicting reports exist about the contribution of phosphorylation of a conserved threonine motif in the β1-tail (β1-pT788/pT789) to integrin activation. We show that widely used and commercially available antibodies against β1-pT788/pT789 integrin do not detect specific β1-pT788/ pT789 integrin signals in immunoblots of severaldoi:10.3929/ethz-b-000527065 fatcat:slyu7xe3xzdjbpi2alkl7mas7m