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The uptake activity ratio for AMP, ADP, and ATP in mutant (T-1) cells of Escherichia coli W, deficient in de novo purine biosynthesis at a point between IMP and 5-aminoimidazole-4-carboxiamide-1--D-ribofuranoside (AICAR), was 1:0.43:0.19. This ratio was approximately equal to the 5 0 -nucleotidase activity ratio in E. coli W cells. The order of inhibitory effect on [2-3 H]ADP uptake by T-1 cells was adenine > adenosine > AMP > ATP. About 2-fold more radioactive purine bases than purinedoi:10.1271/bbb.100063 pmid:21228488 fatcat:qq7pmxeisffcllhglgqpmz7ppq