The Genomic HyperBrowser: inferential genomics at the sequence level

Geir K Sandve, Sveinung Gundersen, Halfdan Rydbeck, Ingrid Glad, Lars Holden, Marit Holden, Knut Liestol, Trevor Clancy, Egil Ferkingstad, Morten Johansen, Vegard Nygaard, Eivind Tostesen (+2 others)
2010 Genome Biology  
The immense increase in the generation of genomic scale data poses an unmet analytical challenge, due to a lack of established methodology with the required flexibility and power. We propose a first principled approach to statistical analysis of sequence-level genomic information. We provide a growing collection of generic biological investigations that query pairwise relations between tracks, represented as mathematical objects, along the genome. The Genomic HyperBrowser implements the approach and is available at http://hyperbrowser.uio.no.
doi:10.1186/gb-2010-11-12-r121 pmid:21182759 pmcid:PMC3046481 fatcat:hlwkdn2t5vakdirac3fvybtmf4