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Micro- and nano-structure based oligonucleotide sensors
<span title="">2015</span>
<i title="Elsevier BV">
<a target="_blank" rel="noopener" href="https://fatcat.wiki/container/ttvkaebpgrb6fiziwhp5jpanv4" style="color: black;">Biosensors & bioelectronics</a>
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This paper presents a review of micro-and nano-structure based oligonucleotide detection and quantification techniques. The characteristics of such devices make them very attractive for Point-of-Care or On-Site-Testing biosensing applications. Their small scale means that they can be robust and portable, their compatibility with modern CMOS electronics means that they can easily be incorporated into hand-held devices and their suitability for mass production means that, out of the different
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... oaches to oligonucleotide detection, they are the most suitable for commercialisation. This review discusses the advantages of micro-and nano-structure based sensors and covers the various oligonucleotide detection techniques that have been developed to date. These include: Bulk Acoustic Wave and Surface Acoustic Wave devices, micro-and nano-cantilever sensors, gene Field Effect Transistors, and nanowire and nanopore based sensors. Oligonucleotide immobilisation techniques are also discussed.
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