Suzuki Cross-Coupling Reactions in Dicationic Room Temperature Ionic Liquid

Chuanyue Zhang, Ruobing Shi, Caiyuan Chen, Chuanming Jin
2013 Youji huaxue  
研究论文 双阳离子型室温离子液体中 Suzuki 偶联反应研究 张传越 石若冰 陈才元 金传明 * (湖北师范学院污染物分析与资源化技术湖北省重点实验室 黄石 435002) 摘要 合成了具有钳子型的双咪唑阳离子核的室温离子液体 2, 它的相转变温度为-51 ℃, 热力学分解温度为 412 ℃, 利用该离子液体作反应溶剂研究了不同钯催化剂 PdCl 2 , Pd(OAc) 2 , Pd-NHC 配合物 3 存在下的 Suzuki 偶联反应. 结 果表明: 在 NaOAc 作碱, 0.5 mol%的 Pd-NHC 配合物 3 存在下溴代苯衍生物与苯硼酸反应具有较高的活性, 产率可以达 到 85%以上, Pd-NHC 配合物 3 催化剂能更好地负载在钳子型双阳离子核室温离子液体 2 中, 该反应体系能重复循环使 用多次, 且分离简单、重现性强、环境友好. 关键词 室温离子液体; Suzuki 偶联反应; N-杂卡宾配合物; 钯 Abstract Room temperature ionic liquid (RTIL) 2 with pincer bisimidazole cationic
more » ... simidazole cationic nuclei was prepared. Its phase transition and thermal decomposition temperature are -51 and 412 ℃, respectively. Suzuki reactions have been studied when different catalyst PdCl 2 , Pd(OAc) 2 , Pd-N-heterocyclic carbene complex 3 were used in RTIL 2. The results indicate that aryl bromide can react with phenylboronic acid in the yield of over 85% in the presence of NaOAc and 0.5 mol% Pd-NHC 3, and the loading capability of Pd-NHC 3 in RTIL 2 is best. This high efficient catalytic system is environmentally benign, recoverable and easily separated with products.
doi:10.6023/cjoc201211002 fatcat:hxbhrvpo2vftfgsbmlkvahuhpe