Pulmonary Metastases from Cervical Adenocarcinoma Regress to a 'Hole' Lot of Nothing

Michael Guandalini, Karin Steinke, Alessandra Francesconi
2009 Journal of Thoracic Oncology  
A 38-year-old woman with recurrent metastatic cervical adenocarcinoma developed innumerable bilateral solid and cavitating pulmonary metastatic nodules. After chemotherapy with paclitaxel and carboplatin, all these nodules regressed to air filled cystic structures with imperceptible walls, pneumatoceles. Immunocompromised patients require close monitoring for development of these as they may be complicated by secondary infection, pneumothorax formation or develop into a tension pneumatocele.
more » ... CUSSION Pulmonary metastases commonly present as solid or cavitating nodules, the latter being described in cases of adenocarcinoma, squamous cell carcinoma, synovial sarcoma, and transitional cell carcinoma. 1,2,4 -9 FIGURE 3. Axial computed tomography (CT) chest (lung window) showing regression of solid and cavitating pulmonary metastases to pneumatoceles (arrows) at (A) carinal and (B) subcarinal levels. Guandalini et al.
doi:10.1097/jto.0b013e3181952947 pmid:19333074 fatcat:qgrj6wo32jhsbhaqphwtnkeb6i