Acute acalculous cholecystitis in children with Epstein–Barr virus infection: a role for Gilbert's syndrome?

Achilleas Attilakos, Alexia Prassouli, George Hadjigeorgiou, Evangelia Lagona, Sofia Kitsiou-Tzeli, Angeliki Galla, Anastasia Stasinopoulou, Themistocles Karpathios
2009 International Journal of Infectious Diseases  
Acute acalculous cholecystitis (AAC) in association with acute Epstein-Barr virus (EBV) infection has rarely been described in childhood. In the literature, there are only four reported pediatric cases of AAC associated with isolated primary EBV infection. We present two cases (one new, one retrospectively reviewed) of children with Gilbert's syndrome (GS) who presented with AAC during the course of primary EBV infection. Antibiotics were not used and AAC subsided gradually as the infection
more » ... essed. The co-occurrence of GS might have played a contributory role in the pathogenesis of AAC during acute EBV infection. #
doi:10.1016/j.ijid.2008.08.009 pmid:19008138 fatcat:pw2ca7dqejhnnhrm7bsj37jpbm