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Quantification of reaction cycle parameters for an essential molecular switch in an auxin-responsive transcription circuit in rice
Proceedings of the National Academy of Sciences of the United States of America
Protein-based molecular switches play critical roles in biological processes. The importance of the prolyl cis−trans switch is underscored by the ubiquitous presence of peptidyl prolyl isomerases such as cyclophilins that accelerate the intrinsically slow isomerization rate. In rice, a tryptophan−proline (W-P) cis−trans switch in transcription repressor protein OsIAA11 along with its associated cyclophilin LRT2 are essential components in a negative feedback gene regulation circuit thatdoi:10.1073/pnas.1817038116 fatcat:4zribsjiefcgnhvzzyvp3ed3ou