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The study involved 30 students with severe bronchial asthma and 30 children with moderate to severe course. Patients with severe bronchial asthma revealed a clear tendency to increase the relative content of interleukin 4 in peripheral blood, which indirectly indicates the severity of inflammation in the bronchi. Almost every second child suffering from severe bronchial asthma reported an increase in the concentration of immunoglobulin E (more than 545.3 IU/ml), and the odds ratio was 1.9 (95%doi:10.22141/2224-05220.127.116.114.75868 doaj:0e783977987b49fbb225e13ca6fb7247 fatcat:bbdfizqoibervlbfsaecstiory