Prediagnostic Human T Lymphotropic Virus Type I Provirus Loads Were Highest in Jamaican Children Who Developed Seborrheic Dermatitis and Severe Anemia

Elizabeth M. Maloney, Masahiro Nagai, Michie Hisada, Samantha S. Soldan, P. Bradley Goebel, Mary Carrington, Takashi Sawada, Meghan B. Brennan, Beverley Cranston, Barrie Hanchard, Steven Jacobson
2004 Journal of Infectious Diseases  
In a recent clinical analysis of 308 Jamaican children, human T lymphotropic virus type I (HTLV-I) infection was found to be associated with significantly higher incidence rates of seborrheic dermatitis, eczema, and persistent hyperreflexia of the lower limbs and with nonsignificantly increased rates of severe anemia and abnormal lymphocytes. Results of examination of HTLV-I viral markers in the 28 HTLV-I-infected children provided virologic support for the epidemiologic associations of HTLV-I
more » ... ith seborrheic dermatitis and severe anemia in childhood. Human T lymphotropic virus type I (HTLV-I) is associated with adult T cell leukemia/lymphoma (ATL) and a neurologic disease called "HTLV-I-associated myelopathy/tropical spastic
doi:10.1086/380567 pmid:14702151 fatcat:djrjmam5kjddvecuttyzgdg4yi