Prevention of radiolysis of monoclonal antibody during labeling

M C Chakrabarti, N Le, C H Paik, W G De Graff, J A Carrasquillo
1996 Journal of Nuclear Medicine  
Monoclonal antibody may undergo loss of immunoreactivity due to radiation damage when labeled with large amounts of 131I or 90Y for therapy. Our aim was to develop a method to protect an antibody during the labeling procedure.
pmid:8708780 fatcat:f2yjhwmzejbofl37xmeazzbjwm