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Cardiac complications in sickle cell disease patients are widely expected. They may be related to iron deposition, anaemia or vasculitis. Hydroxyurea is a known drug that decreases haemoglobin (Hb) S levels. The objective of the study was to assess the effect of hydroxyurea on cardiac sequelae in children with sickle cell disease. Sixty-five sickle cell disease children were enrolled in the study; 37 of them were on regular follow up and hydroxurea treatment, whereas 28 were not. All patientsdoi:10.1097/00043426-199801000-00004 pmid:9482409 fatcat:c5netfcrsncspdnd2uhftbe4r4