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Continuous and pulsed epidemiological models for onchocerciasis with implications for eradication strategy
Mathematical Biosciences and Engineering
Onchocerciasis is an endemic disease in parts of sub-Saharan Africa. Complex mathematical models are being used to assess the likely efficacy of efforts to eradicate the disease; however, their predictions have not always been borne out in practice. In this paper, we represent the immunological aspects of the disease with a single empirical parameter in order to reduce the model complexity. Asymptotic approximation allows us to reduce the vector-borne epidemiological model to a model of andoi:10.3934/mbe.2018038 fatcat:4rns6ertpjcktohoubugfqgbcy