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DNA damage response in monozygotic twins discordant for smoking habits
2012
Mutagenesis
Previous studies in twins indicate that non-shared environment, beyond genetic factors, contributes substantially to individual variation in mutagen sensitivity; however, the role of specific causative factors (e.g. tobacco smoke, diet) was not elucidated. In this investigation, a population of 22 couples of monozygotic twins with discordant smoking habits was selected with the aim of evaluating the influence of tobacco smoke on individual response to DNA damage. The study design virtually
doi:10.1093/mutage/ges062
pmid:23132286
fatcat:cnwygh7q6zhvdf676x7zw757ge