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Treatment for mitochondrial diseases
2020
Reviews in the Neurosciences
AbstractMitochondrial diseases are predominantly caused by mutations of mitochondrial or nuclear DNA, resulting in multisystem defects. Current treatments are largely supportive, and the disorders progress relentlessly. Nutritional supplements, pharmacological agents and physical therapies have been used in different clinical trials, but the efficacy of these interventions need to be further evaluated. Several recent reviews discussed some of the interventions but ignored bias in those trials.
doi:10.1515/revneuro-2020-0034
pmid:32903211
fatcat:pzir5vbsn5gurispl6hh32m6ay