Chemical Properties of Black Rice Yeast Extracts as Pharmaceutical Ingredients for the Management of Type 2 Diabetes mellitus

2021 Tropical Journal of Natural Product Research  
Black rice yeast has the potential to be used as an antidiabetic preparation in type 2 Diabetes mellitus. The study aims to identify the chemical composition of black rice yeast extract obtained from different polar solvents as pharmaceutical ingredients for type 2 Diabetes mellitus (DM). The Black rice flour was macerated using polar solvents (distilled water, methanol, and ethanol). The extracts were investigated for the following parameters: amylum, protein and chromium (III) contents,
more » ... idant activity using the DDPH free radical scavenging assay method and phytochemical profiling using LC-MS. Phytochemical profiling of the different extracts, ethanol, methanol, and water extract, showed 109, 104, and 107 compounds, respectively. The highest concentration of Cr 3 + (0.39%) was found in the freeze-dried water extract. This extract also exhibited the most significant antioxidant activity compared to others. Freeze drying may have protected the bioactive constituents in the extracts from the photooxidation process resulting from drying under the sun. Black rice yeast extract obtained by maceration using polar solvents could be used as pharmaceutical ingredients for type 2 diabetes mellitus.
doi:10.26538/tjnpr/v5i3.13 fatcat:oozyx7nerncllpwhme62z6shlm