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Early-Life Environmental Factors, IFN-γ Methylation Patterns, and Childhood Allergic Rhinitis
2019
International Archives of Allergy and Immunology
While early-life risk factors are known to influence the risk of allergies, the biological mechanisms underlying this observation are unclear. The aim of this study was to examine whether DNA methylation in childhood could underlie the association between early-life risk factors and allergic rhinitis (AR). Methods: In total, 234 patients, aged 6 years, were recruited, i.e., 114 were patients with AR (AR group) and 120 healthy children without AR (NAR group). The DNA methylation patterns of the
doi:10.1159/000495304
fatcat:uliixhs6rfavrput3zgix4sdge