The aim of the research was to evaluate the incidence of breast cancer in the ecological areas of Kazakhstan and assess the potential . A retrospective study of 11 years (1999 to 2009) was conducted using descriptive and analytical methods. The incidence of breast cancer was the lowest in the Aral-Syr Darya area (18.6±0.80/100,000), and highest in the Irtysh area (48.9±1.90/100,000), with an increasing trends over time in almost all areas. A direct strong correlation between the degree of

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... ination with high pollution emissions in the atmosphere from stationary sources and the incidence of breast cancer (r=0.77±0.15; р=0.026). The results indicate an increasing importance of breast cancer in Kazakhstan and an etiological role for environmental pollution.